Effects of cannabidiol on cognition
Effekter av cannabidiol på kognition
Responsible: Johan Franck
Introduction
Increasingly, several lines of evidence point toward the protective effects of cannabidiol (CBD) against the psychotomimetic, cognitively impairing and addictive properties of tetrahyddocannabinol (THC) in cannabis.
Project details
| Inst f klin neurovetenskap (CNS) | |
| Centrum för psykiatriforskning, (CPF), Karolinska Solna | |
| Clinical study | |
| 1 | |
| English | |
| No data/some of the data have been collected. | |
| Ethical permit is required and exists |
Supervisor/Contact
Johan Franck
+46 73 966 0736
johan.franck@ki.se
Contact 2
Amir Englund
+44 789 447 24 60
amir.englund@kcl.ac.uk
Aims
Exciting new research at King’s College, London, will now explore at which relative THC:CBD ratio the harmful effects of cannabis are reduced.
Design
In a cross-over randomised, double-blind study, 45 healthy individuals will attend 4 separate experimental sessions each, and receive vaporised cannabis containing one of the THC:CBD ratios 1:0, 1:1, 1:2, or 1:3.
Material and methods
The participant will be assessed using an extensive cognitive test battery, psychiatric rating scales and measures of mood state. Blood will be collected throughout the day for pharmacokinetic analysis.
Project time schedule
This is an opportunity to work in one of the leading psychiatric research institutes in the world, and learn important skills in human experimental psychopharmacology in a defined and innovative project.
Backup plan
Data from the project already exist and can provide a backup plan.
Teaching/Supervision activities
The candidate would participate in all aspects of the preparatory and experimental protocol, and will also be given the opportunity to analyse online survey data of cannabis users reporting effects from different types of cannabis. Main supervisor is based at KI. Project supervision is provided at King's.